Spanish conceptual artist Plensa draws upon a variety of media in his works, including glass, steel, bronze, water, light, and sound. He is known for both his intimate sculptures as well as large-scale public projects, including the Crown Fountain commission for the Millennium Park, adjacent to the Art Institute of Chicago. In this work, Plensa juxtaposes four danglling, fragile teardroop-shaped glass orbs with its title "androgen," a male hormone.